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Paper # 1

         Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA.

               Chem. Commun. 5386-5388 (2009)

          Linlin Zhao,^†  Yun Zhang,^†  John B. Schenkman,^‡ and James F.. Rusling,^‡†

^†Department of Chemistry, University of Connecticut, U-60, 55 North EagleVille Road, Storrs, Connecticut 06269-3060, and ^‡Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06032

Paper # 2 for:

      Enzyme-DNA Biocolloids for DNA Adduct and Reactive Metabolite Detection by Chromatography-Mass Spectrometry.

                     Anal.Chem. 80:922-932 (2008)

               B. Bajrami,^†  Eli G. Hvastkovs,^† J.B. Schenkman,^‡ and J.F. Rusling^†‡

^†Department of Chemistry, University of Connecticut, Storrs, CT 06269-4060, and ^‡Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030

Paper # 3 for:

                    Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations                          observed in individuals with primary congenital glaucoma.

Pharmacogenetics Genom.  18:665-676 (2008)

   Dharamainder Choudhary,^b Ingela Jansson,^a Mansoor Sarfarazi,^b and John B. Schenkman ^a

Department of Cell Biology,,^a   and  Departments of Surgery,^b University of Connecticut Health Center Farmington, CT 06030 USA

 

Paper # 4 for:

   Electrochemical Genotoxicity Screening for Arylamines Bioactivated by N-Acetyltransferase.     

                Chem. Res. Toxicol. 22:341-347, (2009)

              Linlin Zhao^,† Sadagopan Krishnan^†_, Yun Zhang,^†  John B. Schenkman,^‡ and James F.. Rusling,^‡† 

    ^†Department of Chemistry, 55 North Eagleville Road, University of Connecticut, Storrs, Connecticut 06269, and ^‡Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06032

 

Paper # 5 for:

              Metabolic toxicity of 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK) evaluated using                                     electrochemiluminescent arrays and human CYT P450s.

                        Mol. Biosys. 5:163-169  (2009)

           S. Krishnan,^† E.G. Hvastkovs,^† B. Bajrami,^† J. B. Schenkman,^§ and J. F. Rusling*^†§

     Department of Chemistry^†, 55 North Eagleville Road, University of Connecticut, Storrs, Connecticut 06269, and Department of Cell Biology^§,       University of Connecticut Health Center, Farmington, Connecticut 06032

 

Paper # 6 for:

            CYP1B1,   a developmental gene with a potential role in glaucoma therapy.

                Xenobiotica 39:606-619 (2009)

       D. Choudhary*, I. Jansson^†,  and J.B. Schenkman^†                 

        Department of Cell Biology^† and Surgery*, University of Connecticut Health Center, Farmington, Connecticut 06032

 

Paper # 7 for:

         Characterizing  metabolic inhibition using electrochemical enzyme-DNA biosensors.   

                Anal. Chem. 81:716-724 (2009)

             Dominic O. Hull*, Besnik Bajrami^*, Ingela Jansson†, John B. Schenkman† and James F. Rusling*^,†

           *Department of Chemistry and Institute of Materials Science, University of Connecticut†Department of Cell Biology  ,    University of Connecticut Health Center           

 

^{Selected Papers will be changed periodically Other Relevant Papers}

^{Last modified on 11/05/09}