Dr. John B. Schenkman, the head of this laboratory, received his B.A. in Chemistry in 1960 from Brooklyn College. He trained under W.W. Westerfeld and Dan A. Richert at State University of New York, Upstate Medical Center in Syracuse, N.Y. and received his Ph.D. in Biochemistry in 1964. He then did postdoctoral study under Ronald W. Estabrook at the Johnson Research Foundation of the University of Pennsylvania until 1967. From 1967 to 1968 he was a NSF visiting scientist to the Institute for Protein Research in Osaka, Japan, where he spent a year working with Professor Ryo Sato. Dr. Schenkman spent a subsequent six months in 1968 at the Institut für Toxicologie of the University of Tübingen, in Tübingen, Germany, working with Professor Herbert Remmer. Dr. Schenkman joined the Department of Pharmacology at Yale University School of Medicine, New Haven, Connecticut, as an assistant professor in 1968, rising to the rank of associate professor in 1971. In 1978 he became professor and Head of the Department of Pharmacology at the University of Connecticut Health Center in Farmington, Connecticut. In 1987 he stepped down from the chairmanship and became a professor in that department. In 2001 Dr. Schenkman became Emeritus Professor of Pharmacology. Dr. Schenkman has been engaged in research on various aspects of cytochrome P450 since his postdoctoral studies in 1964. He has published over 150 refereed journal papers on the monooxygenase system and has edited five books on the topic. He has served on the editorial board of a number of biochemistry and pharmacology journals, and been Associate Editor of several. He was an NIH Research Career Developmemt Awardee from 1971-1976, served as a member of the Pharmacology Study Section of NIH and also was a member of the Pharmacological Sciences Review Committee of NIH. Dr. Schenkman has served as Councilor of the American Society of Medical School Pharmacologists, the organization of Pharmacology Chairmen, and as a councilor of the Drug Metabolism Division of the American Society of Pharmacology and Experimental Therapeutics. Although currently a Professor Emeritus, he is still very active in research, frequently performing experiments at the bench. His two current areas of research include involvement of orthologous forms of cytochrome P450 in developmental functions, and development of biosensors for environmental pollutants.